Clinical Trials
Below, are descriptions of clinical trials in which we are currently participating or have recently participated at Southeastern Retina Associates’ three East Tennessee main locations. More information on clinical trials is available at clinicaltrials.gov.
To ask about trials currently enrolling and the requirements to take part, patients or referring physicians may call any of research locations listed below.
Knoxville Based Clinical Trials

Clinical Site Location:
Tennessee Valley Eye Center
140 Capital Dr., Suite 2A
Knoxville, TN 37922
CT Main Number: 865-934-3866
Wet Macular Degeneration
Study: DRCR “Protocol AO” (Treatment Naïve)
Learn MoreStudy: EyeBio/Merck “Super Tuscan”
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Diabetic Retinopathy
Study: DRCR “Protocol AF” (Non-Proliferative DR: Mild to Moderately Severe)
Learn MoreStudy: DRCR “Protocol AFA” (Various levels of DR)
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Macular Telangiectasia Type 2
Study: LMRI “NHOR”
Learn More
Diabetic Macular Edema
Study: EyeBio “BAROLO”
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Branch Retinal Vein Occlusion
Study: EyeBio/Merck "Super Tuscan"
Learn More
Geographic Atrophy
Study: Astellas Pharma "Reveal"
Learn MoreGeographic Atrophy
Study: Gyroscope "Oracle”
Diabetic Macular Edema
Study: EyeBio/Merck "BRUNELLO"
Wet Macular Degeneration
Study: Roche-Genentech “Burgundy”
Chattanooga Based Clinical Trials

1961 Northpoint Blvd
Suite 110
Hixson, TN 37343
CT Main Number: 423-756-1002
Diabetic Macular Edema
Study: EyeBio/Merck "Barolo"
Learn More
Choroidal Melanoma
Study: Aura Biosciences "AU-011-301"
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Geographic Atrophy
Study: K8 for GA
Learn MoreDiabetic Retinopathy
Study: Novo Nordisk A/C “FOCUS”Wet Macular Degeneration
Study: AbbVie “Ascent”
Study: Long-term Follow-UP Study of RGX-314
Tri Cities Based Clinical Trials

Clinical Site Location:
105 Woodlawn Drive,
Johnson City, TN 37604
CT Main Number: 423-464-7436
Geographic Atrophy
Study: Reveal
Sponsor: Astellas Pharma
Learn More
Study: Sienna
Sponser: Regeneron Pharmaceuticals, Inc.
Learn MoreWet Age-Related Macular Degeneration
Study: Ascent
Sponsor: RegenxBio & AbbVie Inc.
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Study: 4FRONT-1
Sponsor: 4D Molecular Therapeutics, Inc.
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Study: Sol-R
Sponsor: Ocular Therapeutix, Inc
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Dry Macular Degeneration/Geographic Atrophy
Study: ARCHER II
Sponsor: Annexon
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Diabetic Macular Edema
Study: Barolo
Sponsor: EyeBiotech Ltd.
Learn MoreMacular Neovascularization
Study: 4FRONT-2
Sponsor: 4D Molecular Therapeutics, Inc.
Learn More
Non-Proliferative Diabetic Retinopathy
Study: Helios-3
Sponsor: Ocular Therapeutix, Inc.
Learn More
Study: Naavigate
Sponsor: RegenxBio & AbbVie Inc.